#DEFINE CATAPLEXY TRIAL#

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'cataplexy.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. cataplexy kat´ah-plekse a condition, often associated with narcolepsy marked by abrupt attacks of muscular weakness and hypotonia triggered by an emotional stimulus, such as mirth, anger, or fear. This condition, called cataplexy (KAT-uh-plek-see), can cause a number of physical changes, from slurred speech to complete weakness of most muscles, and may last up to a few minutes. About 70 of those affected also experience episodes of sudden loss of muscle strength, known as cataplexy. Symptoms often include periods of excessive daytime sleepiness and brief involuntary sleep episodes. 2021 Narcolepsy type 2, in which a person experiences general narcolepsy symptoms but does not have cataplexy. Narcolepsy is a long-term neurological disorder that involves a decreased ability to regulate sleepwake cycles. 2021 The breakthrough designation for AXS-12 being revoked was for cataplexy as a condition in narcolepsy. The word cataplexy means, 'to strike down.' It happens in narcolepsy patients who describe it as sudden attacks of muscle. Cataplexy often affects people who have narcolepsy, a disorder in which there is great difficulty remaining awake during the daytime. 2021 The breakthrough designation for AXS-12 being revoked was for cataplexy as a condition in narcolepsy. Cataplexy is a strange neurologic situation, which is sometimes confused with epilepsy. It is commonly a component of the narcoleptic syndrome alongside daytime sleepiness, sleep paralysis, and vivid hallucinations at the beginning and end of sleep. 2021 While some people may have multiple episodes a day, others may only experience cataplexy once or twice a year. Cataplexy reflects a rapid eye movement (REM)-sleep-related phenomenon involving multiple neurotransmitter systems which regulate sleep and postural muscle tone. 2021 In both cases, more exercise inversely correlated with the degree of sleepiness and frequency of cataplexy episodes experienced. (Zoology) a state of complete absence of movement assumed by animals while shamming death. 2021 People with narcolepsy type 2 may experience all the symptoms of narcolepsy except cataplexy-and their symptoms are often less severe, says the National Institute of Neurological Disorders and Stroke (NINDS). (Pathology) sudden temporary paralysis, brought on by severe shock. 2021 Excessive daytime sleepiness and cataplexy can improve after several weeks of regularly taking sodium oxybate.

#DEFINE CATAPLEXY TRIAL#

Recent Examples on the Web Symptoms such as hallucinations, sleep paralysis, and cataplexy may follow, says Manjamalai Sivaraman, MD, FAASM, a sleep medicine specialist and neurologist at the University of Missouri. The Companys primary focus is on the development and potential FDAapproval for FT218, which is in a Phase 3 clinical trial for the treatment of narcolepsy patients suffering from excessive daytime sleepiness (EDS) and cataplexy.In addition, Avadel develops and markets a portfolio of sterile injectable drugs used in the hospital setting.

Define cataplexy